ABSTRACT
The study was conducted from the patients attending mainly the Medical OPD revealed some fascinating facets. 56.66 % of patients were migrants settled in Delhi from endemic zones, rest of the patients were indigenous. Influx of migrants seemed likely to be risk factors to infection in a densely populated city like Delhi.43.33 % of patients harboured the disease for more then 2 years before initiation of treatment. It denotes the pathetic attitude of the patients. Relapse in 6.66 of case within I year of ALT in PB cases requires review as there is no justification in difference of treatment schedule for PB and MB cases. Chaulmoogra oil dressing in trophic ulcers was found to be very useful and may be extensively tried.
ABSTRACT
Twenty two patients of subacute hepatic failure (SAHF), diagnosed when jaundice progressed for more than 8 weeks with appearance of ascites, with or without encephalopathy, along with biochemical evidence of hepatocellular damage, were studied. The male and female ratio was 4.5:1 and majority (45.4%) of cases were between the age group of 41-50. The mean biochemical values were: S.bilirubin; 9.2 +/- 3.8 mg/dl SGOT; 94.4 +/- 25.0 I.U./lit., SGPT; 107.8 +/- 32.7 I.U./lit., S.Protein; 5.2 +/- 3.5 secs. Ascitic fluid analysis showed transudate in 16 (72.7%) and exudate in 6 (27.2%) patients. Bacterial peritonitis was found in 5 (22.7%) patients. Liver biopsy showed bridging and submassive necrosis. The complications developed in the hospital were: renal failure (36.3%), infection (27.2%), G.I. bleeding (18.1%) and encephalopathy (13.6%). The mortality was (86.3%). Out of 3 (13.6%) patients who survived, only two recovered completely and one had biochemical evidence of hepatocellular necrosis after 6 months of follow up.